| Name | RASGRP2 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL312672 |
| Protein Name | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| Symbol | RASGRP2 |
| Synonyms | CALDAG-GEFI; CDC25L |
| Accession | NM_001098670 |
| Cytogenetic | 11q13 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 69.1 kDa |
| Expression TrueORF Clone | RC212672 |
| Description | RASGRP2 Full-Length MS Protein Standard (NP_001092140), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. |
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