RASGRP2 Full-Length MS Protein Standard


Product Description:

Name RASGRP2 Full-Length MS Protein Standard
Cat# CPFL312672
Protein NameRAS guanyl releasing protein 2 (calcium and DAG-regulated)
SymbolRASGRP2
SynonymsCALDAG-GEFI; CDC25L
AccessionNM_001098670
Cytogenetic11q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW69.1 kDa
Expression TrueORF CloneRC212672
DescriptionRASGRP2 Full-Length MS Protein Standard (NP_001092140), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.

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