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EIF2B4 Full-Length MS Protein Standard


Product Description

NameEIF2B4 Full-Length MS Protein Standard
Protein Nameeukaryotic translation initiation factor 2B, subunit 4 delta
SynonymsEIF-2B; EIF2B; EIF2Bdelta
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionEIF2B4 Full-Length MS Protein Standard (NP_056451), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

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