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IKBKE Full-Length MS Protein Standard


Product Description

NameIKBKE Full-Length MS Protein Standard
Protein Nameinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
SynonymsIKK-E; IKK-i; IKKE; IKKI
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW80.3 kDa
Expression TrueORF CloneRC212481
DescriptionIKBKE Full-Length MS Protein Standard (NP_054721), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 )

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