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AES Full-Length MS Protein Standard

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Product Description


NameAES Full-Length MS Protein Standard
Cat#CPFL312475
Protein Nameamino-terminal enhancer of split
SymbolAES
SynonymsAES-1; AES-2; ESP1; GRG; Grg-5; GRG5; TLE5
AccessionNM_001130
Cytogenetic19p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionAES Full-Length MS Protein Standard (NP_001121), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

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