ADAMTS8 Full-Length MS Protein Standard


Product Description:

Name ADAMTS8 Full-Length MS Protein Standard
Cat# CPFL312446
Protein NameADAM metallopeptidase with thrombospondin type 1 motif, 8
SymbolADAMTS8
SynonymsADAM-TS8; METH2
AccessionNM_007037
Cytogenetic11q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW96.3 kDa
Expression TrueORF CloneRC212446
DescriptionADAMTS8 Full-Length MS Protein Standard (NP_008968), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.

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