ASAH1 Full-Length MS Protein Standard


Product Description:

Name ASAH1 Full-Length MS Protein Standard
Cat# CPFL312434
Protein NameN-acylsphingosine amidohydrolase (acid ceramidase) 1
SymbolASAH1
SynonymsAC; ACDase; ASAH; PHP; PHP32; SMAPME
AccessionNM_004315
Cytogenetic8p22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46.3 kDa
Expression TrueORF CloneRC212434
DescriptionASAH1 Full-Length MS Protein Standard (NP_004306), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.

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