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AMHR2 Full-Length MS Protein Standard

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Product Description


NameAMHR2 Full-Length MS Protein Standard
Cat#CPFL312425
Protein Nameanti-Mullerian hormone receptor, type II
SymbolAMHR2
SynonymsAMHR; MISR2; MISRII; MRII
AccessionNM_020547
Cytogenetic12q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionAMHR2 Full-Length MS Protein Standard (NP_065434), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

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