AMPD3 Full-Length MS Protein Standard


Product Description:

Name AMPD3 Full-Length MS Protein Standard
Cat# CPFL312077
Protein Nameadenosine monophosphate deaminase 3
SymbolAMPD3
SynonymsAMP aminohydrolase; AMP deaminase 3; adenosine monophosphate deaminase 3; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; myoadenylate deaminase; adenosine monophosphate deaminase (isoform E)
AccessionNM_000480
Cytogenetic11p15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW89.5 kDa
Expression TrueORF CloneRC212077
DescriptionAMPD3 Full-Length MS Protein Standard (NP_000471), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

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