AP1B1 Full-Length MS Protein Standard


Product Description:

Name AP1B1 Full-Length MS Protein Standard
Cat# CPFL311920
Protein Nameadaptor-related protein complex 1, beta 1 subunit
SymbolAP1B1
SynonymsADTB1; AP105A; BAM22; CLAPB2
AccessionNM_001127
Cytogenetic22q12.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW104.4 kDa
Expression TrueORF CloneRC211920
DescriptionAP1B1 Full-Length MS Protein Standard (NP_001118), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

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