DICER1 Full-Length MS Protein Standard


Product Description:

Name DICER1 Full-Length MS Protein Standard
Cat# CPFL311804
Protein Namedicer 1, ribonuclease type III
SymbolDICER1
SynonymsDCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2
AccessionNM_030621
Cytogenetic14q32.13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW218.5 kDa
Expression TrueORF CloneRC211804
DescriptionDICER1 Full-Length MS Protein Standard (NP_085124), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

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