CYP11A1 Full-Length MS Protein Standard


Product Description:

Name CYP11A1 Full-Length MS Protein Standard
Cat# CPFL311728
Protein Namecytochrome P450, family 11, subfamily A, polypeptide 1
SymbolCYP11A1
SynonymsCYP11A; CYPXIA1; P450SCC
AccessionNM_001099773
Cytogenetic15q23-q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW42.6 kDa
Expression TrueORF CloneRC211728
DescriptionCYP11A1 Full-Length MS Protein Standard (NP_001093243), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

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