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BTK Full-Length MS Protein Standard

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Product Description


NameBTK Full-Length MS Protein Standard
Cat#CPFL311582
Protein NameBruton agammaglobulinemia tyrosine kinase
SymbolBTK
SynonymsAGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
AccessionNM_000061
CytogeneticXq21.33-q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBTK Full-Length MS Protein Standard (NP_000052), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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