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HDAC4 Full-Length MS Protein Standard

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Product Description


NameHDAC4 Full-Length MS Protein Standard
Cat#CPFL311495
Protein Namehistone deacetylase 4
SymbolHDAC4
SynonymsAHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA
AccessionNM_006037
Cytogenetic2q37.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHDAC4 Full-Length MS Protein Standard (NP_006028), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

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