OPA1 Full-Length MS Protein Standard


Product Description:

Name OPA1 Full-Length MS Protein Standard
Cat# CPFL311417
Protein Nameoptic atrophy 1 (autosomal dominant)
SymbolOPA1
SynonymslargeG; MGM1; NPG; NTG
AccessionNM_130832
Cytogenetic3q29
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW109.4 kDa
Expression TrueORF CloneRC211417
DescriptionOPA1 Full-Length MS Protein Standard (NP_570845), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

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