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KCNE2 Full-Length MS Protein Standard

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Product Description


NameKCNE2 Full-Length MS Protein Standard
Cat#CPFL311320
Protein Namepotassium voltage-gated channel, Isk-related family, member 2
SymbolKCNE2
SynonymsATFB4; LQT5; LQT6; MIRP1
AccessionNM_172201
Cytogenetic21q22.12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKCNE2 Full-Length MS Protein Standard (NP_751951), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.

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