NLRP10 Full-Length MS Protein Standard


Product Description:

Name NLRP10 Full-Length MS Protein Standard
Cat# CPFL311215
Protein NameNLR family, pyrin domain containing 10
SymbolNLRP10
SynonymsCLR11.1; NALP10; NOD8; PAN5; PYNOD
AccessionNM_176821
Cytogenetic11p15.4
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW74.9 kDa
Expression TrueORF CloneRC211215
DescriptionNLRP10 Full-Length MS Protein Standard (NP_789791), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

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