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HNF1A Full-Length MS Protein Standard

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Product Description


NameHNF1A Full-Length MS Protein Standard
Cat#CPFL311201
Protein NameHNF1 homeobox A
SymbolHNF1A
SynonymsHNF-1A; HNF1; IDDM20; LFB1; MODY3; TCF-1; TCF1
AccessionNM_000545
Cytogenetic12q24.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHNF1A Full-Length MS Protein Standard (NP_000536), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5-GTTAATNATTAAC-3. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.

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