KDM4C Full-Length MS Protein Standard


Product Description:

Name KDM4C Full-Length MS Protein Standard
Cat# CPFL311182
Protein Namelysine (K)-specific demethylase 4C
SymbolKDM4C
SynonymsGASC1; JHDM3C; JMJD2C; TDRD14C
AccessionNM_015061
Cytogenetic9p24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW119.8 kDa
Expression TrueORF CloneRC211182
DescriptionKDM4C Full-Length MS Protein Standard (NP_055876), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

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