PDE10A Full-Length MS Protein Standard


Product Description:

Name PDE10A Full-Length MS Protein Standard
Cat# CPFL311181
Protein NamePDE10A phosphodiesterase 10A
SymbolPDE10A
SynonymsFLJ11894; FLJ25677; HSPDE10A
AccessionNM_006661
Cytogenetic6q26
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW88.2 kDa
Expression TrueORF CloneRC211181
DescriptionPDE10A Full-Length MS Protein Standard (NP_006652), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5 monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

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