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KIRREL3 Full-Length MS Protein Standard

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Product Description


NameKIRREL3 Full-Length MS Protein Standard
Cat#CPFL311025
Protein Namekin of IRRE like 3 (Drosophila)
SymbolKIRREL3
SynonymsKIRRE; MRD4; NEPH2; PRO4502
AccessionNM_032531
Cytogenetic11q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKIRREL3 Full-Length MS Protein Standard (NP_115920), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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