PDE4B Full-Length MS Protein Standard


Product Description:

Name PDE4B Full-Length MS Protein Standard
Cat# CPFL310912
Protein NamePDE4B phosphodiesterase 4B, cAMP-specific
SymbolPDE4B
SynonymsDPDE4; PDE4B5; PDEIVB
AccessionNM_001037341
Cytogenetic1p31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW83.2 kDa
Expression TrueORF CloneRC210912
DescriptionPDE4B Full-Length MS Protein Standard (NP_001032418), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.

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