SART3 Full-Length MS Protein Standard


Product Description:

Name SART3 Full-Length MS Protein Standard
Cat# CPFL310837
Protein Namesquamous cell carcinoma antigen recognized
SymbolSART3
SynonymsDSAP1; P100; p110; p110(nrb); RP11-13G14; TIP110
AccessionNM_014706
Cytogenetic12q24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW109.8 kDa
Expression TrueORF CloneRC210837
DescriptionSART3 Full-Length MS Protein Standard (NP_055521), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

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