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DSCR3 Full-Length MS Protein Standard

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Product Description


NameDSCR3 Full-Length MS Protein Standard
Cat#CPFL310755
Protein NameDown syndrome critical region gene 3
SymbolDSCR3
SynonymsDCRA; DSCRA
AccessionNM_006052
Cytogenetic21q22.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDSCR3 Full-Length MS Protein Standard (NP_006043), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.

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