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ZWINT Full-Length MS Protein Standard

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Product Description


NameZWINT Full-Length MS Protein Standard
Cat#CPFL310692
Protein NameZW10 interactor
SymbolZWINT
SynonymsHZwint-1; KNTC2AP; SIP30; ZWINT1
AccessionNM_007057
Cytogenetic10q21-q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionZWINT Full-Length MS Protein Standard (NP_008988), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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