TSTA3 Full-Length MS Protein Standard


Product Description:

Name TSTA3 Full-Length MS Protein Standard
Cat# CPFL310643
Protein Nametissue specific transplantation antigen P35B
SymbolTSTA3
SynonymsFX; P35B; SDR4E1
AccessionNM_003313
Cytogenetic8q24.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW35.7 kDa
Expression TrueORF CloneRC210643
DescriptionTSTA3 Full-Length MS Protein Standard (NP_003304), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

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