FKBP5 Full-Length MS Protein Standard


Product Description:

Name FKBP5 Full-Length MS Protein Standard
Cat# CPFL310608
Protein NameFK506 binding protein 5
SymbolFKBP5
SynonymsAIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10
AccessionNM_004117
Cytogenetic6p21.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW51 kDa
Expression TrueORF CloneRC210608
DescriptionFKBP5 Full-Length MS Protein Standard (NP_004108), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

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