JAG1 Full-Length MS Protein Standard


Product Description:

Name JAG1 Full-Length MS Protein Standard
Cat# CPFL310516
Protein Namejagged 1
SymbolJAG1
SynonymsAGS; AHD; AWS; CD339; HJ1; JAGL1
AccessionNM_000214
Cytogenetic20p12.1-p11.23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW133.6 kDa
Expression TrueORF CloneRC210516
DescriptionJAG1 Full-Length MS Protein Standard (NP_000205), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

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