MC2R Full-Length MS Protein Standard


Product Description:

Name MC2R Full-Length MS Protein Standard
Cat# CPFL310483
Protein Namemelanocortin 2 receptor (adrenocorticotropic hormone)
SymbolMC2R
SynonymsACTHR
AccessionNM_000529
Cytogenetic18p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW33.7 kDa
Expression TrueORF CloneRC210483
DescriptionMC2R Full-Length MS Protein Standard (NP_000520), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.

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