PDCD1 Full-Length MS Protein Standard


Product Description:

Name PDCD1 Full-Length MS Protein Standard
Cat# CPFL310364
Protein NamePdcd1 programmed cell death 1
SymbolPDCD1
SynonymsCD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
AccessionNM_005018
Cytogenetic2q37.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW29.2 kDa
Expression TrueORF CloneRC210364
DescriptionPD-1 / PDCD1 Full-Length MS Protein Standard (NP_005009), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

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