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GNA11 Full-Length MS Protein Standard

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Product Description


NameGNA11 Full-Length MS Protein Standard
Cat#CPFL310292
Protein NameGNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [ Homo sapiens ]
SymbolGNA11
SynonymsFBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2
AccessionNM_002067
Cytogenetic19p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGNA11 Full-Length MS Protein Standard (NP_002058), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

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