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MARCKS Full-Length MS Protein Standard

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Product Description


NameMARCKS Full-Length MS Protein Standard
Cat#CPFL310277
Protein Namemyristoylated alanine-rich protein kinase C substrate
SymbolMARCKS
Synonyms80K-L; MACS; PKCSL; PRKCSL
AccessionNM_002356
Cytogenetic6q22.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMARCKS Full-Length MS Protein Standard (NP_002347), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

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