HIST1H2AC Full-Length MS Protein Standard


Product Description:

Name HIST1H2AC Full-Length MS Protein Standard
Cat# CPFL310259
Protein Namehistone cluster 1, H2ac
SymbolHIST1H2AC
SynonymsdJ221C16.4; H2A/l; H2AFL
AccessionNM_003512
Cytogenetic6p22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW13.9 kDa
Expression TrueORF CloneRC210259
DescriptionHIST1H2AC Full-Length MS Protein Standard (NP_003503), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

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