DSCR4 Full-Length MS Protein Standard


Product Description:

Name DSCR4 Full-Length MS Protein Standard
Cat# CPFL310247
Protein NameDown syndrome critical region gene 4
SymbolDSCR4
SynonymsDCRB; DSCRB
AccessionNM_005867
Cytogenetic21q22.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW12.8 kDa
Expression TrueORF CloneRC210247
DescriptionDSCR4 Full-Length MS Protein Standard (NP_005858), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta.

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