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CA8 Full-Length MS Protein Standard

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Product Description


NameCA8 Full-Length MS Protein Standard
Cat#CPFL310228
Protein Namecarbonic anhydrase VIII
SymbolCA8
SynonymsCA-VIII; CALS; CAMRQ3; CARP
AccessionNM_004056
Cytogenetic8q12.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCA8 Full-Length MS Protein Standard (NP_004047), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.

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