DEFA5 Full-Length MS Protein Standard


Product Description:

Name DEFA5 Full-Length MS Protein Standard
Cat# CPFL310219
Protein Namedefensin, alpha 5, Paneth cell-specific
SymbolDEFA5
SynonymsDEF5; HD-5
AccessionNM_021010
Cytogenetic8p23.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW8.1 kDa
Expression TrueORF CloneRC210219
DescriptionDEFA5 Full-Length MS Protein Standard (NP_066290), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

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