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PDE6H Full-Length MS Protein Standard

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Product Description


NamePDE6H Full-Length MS Protein Standard
Cat#CPFL310215
Protein Namephosphodiesterase 6H, cGMP-specific, cone, gamma
SymbolPDE6H
SynonymsACHM6; RCD3
AccessionNM_006205
Cytogenetic12p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPDE6H Full-Length MS Protein Standard (NP_006196), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A).

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