ABO Full-Length MS Protein Standard


Product Description:

Name ABO Full-Length MS Protein Standard
Cat# CPFL310203
Protein NameABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
SymbolABO
SynonymsA3GALNT; A3GALT1; GTB; NAGAT
AccessionNM_020469
Cytogenetic9q34.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW40.8 kDa
Expression TrueORF CloneRC210203
DescriptionABO Full-Length MS Protein Standard (NP_065202), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The O blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

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