FGF23 Full-Length MS Protein Standard


Product Description:

Name FGF23 Full-Length MS Protein Standard
Cat# CPFL310127
Protein Namefibroblast growth factor 23
SymbolFGF23
SynonymsADHR; FGFN; HPDR2; HYPF; PHPTC
AccessionNM_020638
Cytogenetic12p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW25.3 kDa
Expression TrueORF CloneRC210127
DescriptionFGF23 Full-Length MS Protein Standard (NP_065689), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

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