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FGF23 Full-Length MS Protein Standard

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Product Description


NameFGF23 Full-Length MS Protein Standard
Cat#CPFL310127
Protein Namefibroblast growth factor 23
SymbolFGF23
SynonymsADHR; FGFN; HPDR2; HYPF; PHPTC
AccessionNM_020638
Cytogenetic12p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionFGF23 Full-Length MS Protein Standard (NP_065689), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

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