AGL Full-Length MS Protein Standard


Product Description:

Name AGL Full-Length MS Protein Standard
Cat# CPFL310005
Protein Nameamylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
SymbolAGL
SynonymsGDE
AccessionNM_000642
Cytogenetic1p21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW174.6 kDa
Expression TrueORF CloneRC210005
DescriptionAGL Full-Length MS Protein Standard (NP_000633), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.

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