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IRF3 Full-Length MS Protein Standard

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Product Description


NameIRF3 Full-Length MS Protein Standard
Cat#CPFL309951
Protein Nameinterferon regulatory factor 3
SymbolIRF3
SynonymsMGC94729; interferon regulatory factor 3
AccessionNM_001571
Cytogenetic19q13.3-q13.4
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIRF3 Full-Length MS Protein Standard (NP_001562), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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