YWHAZ Full-Length MS Protein Standard


Product Description:

Name YWHAZ Full-Length MS Protein Standard
Cat# CPFL309909
Protein Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
SymbolYWHAZ
Synonyms14-3-3-zeta; HEL-S-3; HEL4; KCIP-1; YWHAD
AccessionNM_003406
Cytogenetic8q23.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW27.6 kDa
Expression TrueORF CloneRC209909
DescriptionYWHAZ Full-Length MS Protein Standard (NP_003397), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5 UTR but that encode the same protein have been identified for this gene.

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