FTH1 Full-Length MS Protein Standard


Product Description:

Name FTH1 Full-Length MS Protein Standard
Cat# CPFL309845
Protein Nameferritin, heavy polypeptide 1
SymbolFTH1
SynonymsFHC; FTH; FTHL6; HFE5; PIG15; PLIF
AccessionNM_002032
Cytogenetic11q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW21 kDa
Expression TrueORF CloneRC209845
DescriptionFTH1 Full-Length MS Protein Standard (NP_002023), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

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