KAT2B Full-Length MS Protein Standard


Product Description:

Name KAT2B Full-Length MS Protein Standard
Cat# CPFL309821
Protein NameK(lysine) acetyltransferase 2B
SymbolKAT2B
SynonymsCAF; P/CAF; PCAF
AccessionNM_003884
Cytogenetic3p24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW92.8 kDa
Expression TrueORF CloneRC209821
DescriptionKAT2B Full-Length MS Protein Standard (NP_003875), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

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