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RGCC Full-Length MS Protein Standard

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Product Description


NameRGCC Full-Length MS Protein Standard
Cat#CPFL309810
Protein Nameregulator of cell cycle
SymbolRGCC
SynonymsbA157L14.2; C13orf15; RGC-32; RGC32
AccessionNM_014059
Cytogenetic13q14.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionC13orf15 Full-Length MS Protein Standard (NP_054778), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression.

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