IL23A Full-Length MS Protein Standard


Product Description:

Name IL23A Full-Length MS Protein Standard
Cat# CPFL309680
Protein Nameinterleukin 23, alpha subunit p19
SymbolIL23A
SynonymsIL-23; IL-23A; IL23P19; P19; SGRF
AccessionNM_016584
Cytogenetic12q13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW18.6 kDa
Expression TrueORF CloneRC209680
DescriptionIL23A Full-Length MS Protein Standard (NP_057668), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.

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