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HDAC6 Full-Length MS Protein Standard

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Product Description


NameHDAC6 Full-Length MS Protein Standard
Cat#CPFL309649
Protein Namehistone deacetylase 6
SymbolHDAC6
SynonymsCPBHM; HD6; JM21; PPP1R90
AccessionNM_006044
CytogeneticXp11.23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHDAC6 Full-Length MS Protein Standard (NP_006035), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

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