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DNASE2 Full-Length MS Protein Standard

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Product Description


NameDNASE2 Full-Length MS Protein Standard
Cat#CPFL309573
Protein Namedeoxyribonuclease II, lysosomal
SymbolDNASE2
SynonymsDNASE2A; DNL; DNL2
AccessionNM_001375
Cytogenetic19p13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDNASE2 Full-Length MS Protein Standard (NP_001366), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

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