KRT8 Full-Length MS Protein Standard


Product Description:

Name KRT8 Full-Length MS Protein Standard
Cat# CPFL309570
Protein Namekeratin 8
SymbolKRT8
SynonymsCARD2; CK-8; CK8; CYK8; K2C8; K8; KO
AccessionNM_002273
Cytogenetic12q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW53.5 kDa
Expression TrueORF CloneRC209570
DescriptionKRT8 Full-Length MS Protein Standard (NP_002264), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

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