LLGL2 Full-Length MS Protein Standard


Product Description:

Name LLGL2 Full-Length MS Protein Standard
Cat# CPFL309559
Protein Namelethal giant larvae homolog 2
SymbolLLGL2
SynonymsHGL; Hugl-2; LGL2
AccessionNM_001031803
Cytogenetic17q25.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW113.3 kDa
Expression TrueORF CloneRC209559
DescriptionLLGL2 Full-Length MS Protein Standard (NP_001026973), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the proteins ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

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