| Name | LLGL2 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL309559 |
| Protein Name | lethal giant larvae homolog 2 |
| Symbol | LLGL2 |
| Synonyms | HGL; Hugl-2; LGL2 |
| Accession | NM_001031803 |
| Cytogenetic | 17q25.1 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 113.3 kDa |
| Expression TrueORF Clone | RC209559 |
| Description | LLGL2 Full-Length MS Protein Standard (NP_001026973), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the proteins ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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