NOB1 Full-Length MS Protein Standard


Product Description:

Name NOB1 Full-Length MS Protein Standard
Cat# CPFL309537
Protein NameNIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
SymbolNOB1
SynonymsART-4; MST158; MSTP158; NOB1P; PSMD8BP1
AccessionNM_014062
Cytogenetic16q22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46.5 kDa
Expression TrueORF CloneRC209537
DescriptionNOB1 Full-Length MS Protein Standard (NP_054781), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 )

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